Research published last month in the Society of Neuroscience, and discussed here by New Scientist Magazine, show growing support for the belief that Parkinson's disease begins in the gut and that synuclein fibres can travel from the gut to the brain, as seen in mice; challenging the long held belief that brain is protected from such transfer. While unable to yet determine the specific microbe responsible, this research is a step forward that can inform earlier diagnosis and treatment of Parkinson's by providing direction for future research.