Artificial grafts, which are commonly used in kidney dialysis patients, currently lead to approximately 50% of patients experiencing complications. These complications are typically due to the need to connect the vein and artery using an artificial tube. Scientists at University of Minnesota recently announced the development of a lab-grown blood vessel that when implanted, may become repopulated with cells by the recipient. This development may have applications in kidney dialysis, coronary and peripheral bybass blood vessels and tublar heart valves. A test of the vessels, which used adult baboons, found that the grafts appeared like a blood vessel after being implanted, and observed healthy cells from the baboon taking up residence inside the walls of the tubes. Six months after the initial implant, the same baboons were able to withstand almost 30 times the average human blood pressure without bursting. Scientists are now working to use these lab-grown blood vessels in children with pediatric heart defects.
created a lab-grown blood vessel replacement composed of biological materials, but without living cells at implantation